Guns N' Roses – Welcome to the Jungle is one of the most iconic albums of all time. In a time when systemic injustice is once again at the forefront of public consciousness, “Bulls on Parade” remains as relevant as ever.Ģ4. It's a powerful and cathartic experience, and it's no wonder that the song has become an anthem for social justice movements around the world. The guitars chug and grind like an advancing tank, while Zack de la Rocha's vocals are filled with righteous indignation. The song opens with the sounds of gunfire and an air raid siren, setting the stage for an onslaught of sonic fury. Rage Against The Machine – Bulls on Paradeįew songs are as overtly political as Rage Against the Machine's “Bulls on Parade.” The song, which was released in 1996, is a searing indictment of the American military-industrial complex, and its lyrics unapologetically denounce the government's role in propagating violence and oppression. She even references the ultimate warm-up song, Survivor’s “Eye Of The Tiger,” when she sings “I got the eye of the tiger, a fighter/Dancing through the fire/’Cause I am a champion, and you’re gonna hear me roar.” It’s perfect pep rally material.25. Some of the best homecoming songs are empowering, something you can really rally around, and Katy Perry’s “Roar” is just that. With its blast of horns, it also evoked the school spirit, but when Beyoncé performed it live with a full marching band at Coachella for her Homecoming: The Live Album, it became a stadium anthem. 4: Beyoncé: Crazy In Love – Homecoming Liveĭeclared “the best pop single of the 21st Century” by NME in 2013, Beyoncé’s “Crazy In Love” has been a ubiquitous presence at every homecoming event (any event, really) since its release in 2003, and is still a go-to hit to get people’s pulses pumping. With another epic guitar intro, “Thunderstruck” builds up tension before exploding into a full singalong. This one’s definitely for the tailgaters and loyal alumni who like to slam on the bleachers and yell “Thunder!” along with the Young brothers at every home game. Over a decade after its release, we gotta feeling this song still gets the job done.Ĭlick to load video 5: AC/DC: Thunderstruck There was a period when The Black Eyed Peas’ electro-rap anthem “Gotta Feeling,” from their 2009 album, The END, dominated pop culture: from commercials to sports stadiums, weddings to homecomings, their irrepressible hit was a sure-fire way to fire people up. Each generation gets its own dance-craze hits, from the “Electric Slide” to the “Percolator” the mid-00s had the “Cupid Shuffle,” an infectiously catchy dance-pop hit that’s beloved by all ages. You have to love songs that give exact choreography instructions, especially for those of us not blessed with natural dance skills. There’s one song that’s quintessentially 80s but sounded like nothing else on the chart: “Come On Eileen.” Without a synth in sight, nothing revs up a dancefloor or tailgate then a couple of banjos, accordions, and fiddles. Click to load video 14: Dexys Midnight Runners: Come On Eileenįor anyone who came of age during the 80s, your homecoming soundtrack probably sounded a lot like a John Hughes’ movie, with plenty of OMD, a-ha, and Madonna.
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We reinvented this mechanic to fit into Curse: to unlock the chest you have to kill a certain number of enemies in the room without getting hit. In Dead Cells, when you open a cursed chest, you are inflicted with a curse that lasts until you kill a certain number of enemies. Now, the Cursed Chest from Dead Cells gives you a third way. In Curse, there used to be two ways to get a cursed item (weapon or relic): get one at a starting altar or buy one at a sanctuary. We took some liberties with the Cursed Chest. If that doesn’t fit Curse’s penchant for tempting players to their own doom, we don’t know what does! The Sword of Conjunctivius (see screenshot below) is a real devil – get hit once, and you’re toast. Both swords have the same effect as in Dead Cells. In Curse, we called these weapons the Broadsword of the Knight, the Sword of Conjunctivius, and the Crossbow of the Condemned. The Cursed Sword was a must, for obvious reasons. The crossbow is an entirely new weapon in Curse, which made it even more alluring to us. We started with a rather long list of badass Dead Cells weapons and then filtered it down until we had only the most iconic ones that also made the most sense for Curse: The Broadsword, the Cursed Sword, and the Explosive Crossbow. Each new item and mechanic introduced in this update fits into our universe.ĭeciding which weapons to take from Dead Cells was a fun process. That’s why we wanted to keep the content lore-friendly and fit the general vibe of Curse as well. We were also aware that some players don’t like crossovers, since it can pull them out of the world. This didn’t work as well for Curse, so we changed it to something we believe is true to both worlds – slightly less comedic, but still somewhat alien and quirky. In Dead Cells for example, the Cursed Chest speaks to the player, pleading them to open it. This also goes for the artistic direction, where Dead Cells has a somewhat cartoony, comedic vibe, which isn’t present in Curse. To that end, we’ve added new weapons, originally from Dead Cells, the Cursed Chest, and the Prisoner’s head skin for McCallister, Curse of the Dead Gods’ main character.įrom a game design perspective it was a very interesting challenge because it meant taking elements of two similar but also different games and mashing them together. Today, we’re doing a deep dive into how we crafted the Curse of the Dead Cells Update, a collaboration between us and Dead Cells’ developers, Motion Twin and Evil Empire.ĭeath in Curse is the gift that keeps on giving, and in this new update, we’re excited to deliver new ways for you to reach your unique fate. As thankful as we are for the response, we’re equally excited to show you new things. Curse of the Dead Gods released on PlayStation 4 last month, and all of us here at Passtech Games have been glued to our screens watching all your amazing footage, feedback, and reactions. Play a wide variety of traditional jigsaw puzzles in Classic Jigsaw mode. With multiple game modes, downloadable puzzle packs, and the ability to create your own custom puzzles, you will never run out of things to do in Microsoft Jigsaw! Classic Jigsaw Mode No matter where you play, escape on a peaceful journey in Mahjong by Microsoft, on Windows or Mobile. Bookmark your favorite puzzle boards to play again and again. Turn on the timer to challenge your speed, or play at your own pace, unlocking backgrounds and tile sets as you progress. Play five Daily Challenges offering additional game modes like Classic, Golden Tiles, Lightning Tiles, Match Attack and Score Attack. Earn badges for the number of challenges you complete each month. Daily Challenges offer unique game play modes like Golden Tiles, where your only goal is to uncover and match the hidden pairs of golden tiles. On Windows 11:Ĭhoose from four levels of difficulty, perfect for Mahjong beginners and experts alike. Sign in with your Xbox account to collect achievements, save your progress, and climb the leaderboard in each game. Complete Daily Challenges to earn monthly badges, use hints or the undo feature, and enjoy unique themes and tile sets as you solve hundreds of puzzles in the popular game of strategy, memory, and skill. Relax as you earn points completing beautiful mahjong puzzles. Or take the tranquil play of Mahjong with you with our mobile app, Mahjong by Microsoft – available on iOS or Android. Log in with your Xbox account to earn achievements, compete with your friends, submit your scores to the leaderboards, and save your statistics and games in the cloud!Įnjoy gorgeous graphics, relaxing sounds, and the tile-matching fun of Mahjong on Windows 11. Now you can even create custom themes from your own photos! Xbox Integration The Microsoft Solitaire Collection features several beautiful themes, from the simplicity of "Classic" to the serenity of an Aquarium that comes to life before you while you play. Complete enough Daily Challenges in a month to earn badges and compete with your friends. See how many boards you can clear and how high you can score in this highly addictive card game! Daily Challenges Pair two cards that add up to 13 in order to remove them from the board. How many boards can you clear before you run out of deals? Pyramid Select cards in a sequence, either up or down, to earn points and clear the board. More strategic than the Klondike version, FreeCell rewards players who think several moves ahead. Use four extra cells to move cards around as you try to clear all cards from the table. Start out playing with a single suit until you’re comfortable, and then see how you fare when using two or even all four suits in a game. SpiderĮight columns of cards await your attempts to clear them with the fewest moves possible. Try to clear all the cards from the table using one or three-card draw, while using traditional scoring or the Vegas scoring system. This version is the timeless classic that many people just call "Solitaire". With new features, collections, daily challenges and monthly events, Microsoft Solitaire Collection continues to be a digital sensation. Simple rules and straightforward gameplay make it easy for anyone to pick up and play. Thank you for your continued passion and love of play! We are proud to be part of your daily choice of games.Ĭelebrating over 30 Years (since 1990) - Microsoft Solitaire remains one of the most played video games of ALL TIME! Simple rules and straightforward gameplay deliver fun for everyone. Microsoft Solitaire remains the most played video game of ALL TIME! Inducted into the Video Game Hall of Fame in 2019, millions of players choose Microsoft Casual Games because we offer the best experiences for anyone from age 8 to 108. We are thrilled to have celebrated the 30th Anniversary of two of our most beloved games - Microsoft Minesweeper (1989) and Microsoft Solitaire (1990). Whether you play on Windows 11, iOS, Android, or Web, we believe in building community through fun. The Microsoft Casual Games Studio has revolutionized the most popular genres of casual games, bringing a fresh twist to classic favorites that have been delighting fans for OVER 30 years! With features like Daily Challenges, Events, Collections, Achievements and Rewards, we are dedicated to delivering great casual game experiences for players of all ages.Īs a collaborative team who loves making games as much as we love playing them, we work hard to add new content and excitement for players to enjoy around the world. She may have been dismissed as ‘just a gonzo girl’ until then, but after she became Wonder Woman, the entire industry realized what she had been all along: a fucking superstar.” “The movie ended up being a huge hit, but while that experience gave me PTSD and made me drastically change my approach to filmmaking, the memories of working with Romi will always hold a special place in my heart, just like she does. “Day after grueling day, she conducted herself with grace, class, patience, courage and incredible professionalism, all the while not only delivering a career-defining performance, but also showing everybody what an absolute badass she was,” Braun says. And boy, did she keep her word.”ĭespite Justice League XXX becoming what Braun calls “the biggest nightmare of my 30-plus year career,” Rain proved to be “the glue that held the entire production together.” ‘Thank you for this amazing opportunity, Axel. “That ’s how much she cared about my project. When they met in person a week later and he told her she got the part, “she literally burst into tears,” Braun adds. “She had memorized a lengthy monologue, and she conveyed so much raw emotion, strength and charisma that I instantly knew I had found my lead.” “It was nothing short of incredible,” Braun continues. “I had only shot Romi once, in an all-sex movie a few years prior, but I suddenly recalled bumping into her at the AVN Awards earlier that year, and that she told me, ‘Hey Axel, keep me in mind for one of your parodies… I know everybody thinks I ’m just a gonzo girl, but I ’m a pretty damn good actress!’īraun asked her agent at the time to have Rain come to his office for an audition but she was out of the country and had to submit a video. Then he remembered his conversation with Rain. Which is why, after an extensive casting call that saw more than 100 girls show up to audition at the Wicked offices on a Sunday afternoon, I still found myself without the perfect Wonder Woman.” Finding people who can act and give a strong sexual performance is not easy, but finding ones who look exactly like a specific character and are willing to endure my notoriously long days on set is near impossible. “As with all my parodies, casting was crucial. “It was the spring of 2017, and I was getting ready to shoot what was my biggest undertaking to date: Justice League XXX,” Braun tells AVN. Rain took the initiative with four-time AVN Director of the Year Axel Braun, who recalls how she spoke up when they crossed paths in Las Vegas.īraun chose Rain for the lead role of Wonder Woman in Justice League XXX, a Wicked Pictures production that would go on to win the 2018 AVN Award for Best Parody, along with five other honors. I like to say what I want and go after what I want. “That’s probably the Boston Italian thing. “Fortune favors the brave and the prepared-you’ve gotta go for it,” Rain reasons. When she made up her mind to do something, she didn’t wait for something to be handed to her. If there was any luck involved, without question Rain took the necessary actions to make her own. I pursued everything but there is also a degree of luck and timing.” “I’m so grateful and I still consider myself lucky. It’s crazy to be at this point where I can hire people who used to book me. “I’m so happy I’ve contributed to the industry my whole life, so happy to be involved in so much of it. I never thought I could do as much as I’ve done. “It still brings a little bit of tears to my eyes. “That to me is a dream come true-my adult life’s work,” Rain tells AVN. Her remarkable run also includes becoming a certified sex educator, brand ambassador, Fleshlight Girl, podcaster and hosting the 2019 AVN Awards in what has turned into a future Hall of Fame resume. One of the prominent faces of the new era of adult entertainment, where empowered performers manage their brands on multiple platforms while engaging a global fanbase through social media, the ambitious native of Boston continues to demonstrate what’s possible in the business of pleasure.įrom nude modeling and exotic dancing to webcamming and headlining hundreds of adult movies, Rain has excelled at every phase of the game. More than a decade later, the results speak for themselves. I want to have covers… I want to have opportunities.” “I said if I’m going to do this, I want to do it right. “I always had the mentality of trying to take it seriously and make it into a career,” Rain says. LOS ANGELES - Romi Rain came into the adult industry armed with plans to create a legacy. This is the cover story of the June issue of AVN magazine.
For instance, opiate abusers may find it helpful to begin their abstinence with a brief but intensive outpatient opiate drug detox in Sahuarita. Programs typically meet at the clinic a couple of times every week for a few hours at a time.Ĭertain programs provide a combination of the in/out approach: Inpatient for medical stabilization, partial hospitalization for moderate cases, intensive outpatient programs, and outpatient clinics for follow-up. Outpatient treatment programs in Sahuarita provide flexibility to those who are unable to take time away from their regular lives, work or school. Stephen Remolina is a psychiatrist in Oro Valley, AZ, and is affiliated with Sonora Behavioral Health. Located in Tucson, Sonora provides the comprehensive care needed to successfully manage mental health disorders and lead a life of recovery. Full treatment services, including medical and behavioral therapy, are provided all at one location. General Psychiatry, Child & Adolescent Psychiatry. Sonora Behavioral Health Hospital is dedicated to providing superior treatment to children, teens, and adults suffering from schizophrenia. Residential inpatient treatment in Sahuarita consists of 24-hour care at a live-in facility. Stephen Remolina is a psychiatrist in Oro Valley, Arizona and is affiliated with Sonora Behavioral Health Hospital.He received his medical degree from Ross University School of Medicine and. The first step towards recovery usually requires clients to detox in Sahuarita under medical supervision, and follow-up with a period of intensive therapy at the center. They help hospitals maintain their donation programs by. Additionally, the signs and symptoms of ODD will vary from child to child, with noted differences in how symptoms present in girls as opposed to how they present in boys.Clients who are looking for Drug Rehab in Sahuarita or Alcohol Rehab in Sahuarita can find help at a treatment center. Our Donor Program Development coordinators are a resource for more than 120 hospitals in Arizona. Our three adult units service those over the age of 18. inconsistent discipline)Īt times it can be difficult to distinguish between a child who is just headstrong or disobedient at times and one who is experiencing oppositional defiant disorder. Sonora Behavioral Health Hospital is the leading provider in Tucson of treatment programs for adults suffering from mental health, chemical dependence or dual diagnosis. Lack of parental involvement / inconsistent parenting (e.g. Sonora Behavioral Health Hospital is dedicated to providing superior treatment to children, teens, and adults suffering from co-occurring disorders.Certain situations such as domestic violence, sexual abuse, or poor quality of life can cause ODD in children who have unstable levels of or neurotransmitters or a genetic predisposition to the disorder. These chemical changes are what cause some of the symptoms of ODD like irritability, no fear of punishment, and engagement of hostile behaviors.Įnvironmental: Environmental factors at home and school play a crucial role in the development of oppositional defiant disorder. Sonora Behavioral Health is a provider established in Tucson, Arizona operating as a Psychiatric Hospital. Higher or lower levels of neurotransmitters can cause sudden changes in mood and thinking processes due to the impaired transmission of nerve impulses. Physical: The presence of oppositional defiant disorder is often associated with changes in the neurotransmitters in the brain. Adventist Health Sonora provides professional, compassionate behavioral healthcare services for people dealing with a variety of mental health issues. Emergency Psychiatric Services Yes Psychiatric Outpatient Services Yes Psychiatric Intensive Outpatient Services Yes. Genetic: It has been shown that ODD is likely a hereditary condition and that if an individual has a close relative with this mental illness, they have a predisposition to the development of oppositional defiant disorder. Sonora Behavioral Health Hospital in Tucson, AZ is a psychiatric facility. The following are some examples of the different causes and factors that may be attributed to the development of ODD: Sonora Behavioral Health Hospital provides inpatient behavioral health and chemical dependency services for children, adolescents, and adults. However, extensive studies have shown that this disorder is most likely the combination of biological, genetic, and environmental factors. To date researchers are unable to conclusively identify one exact cause for the development of oppositional defiant disorder. The addition of a complement-fixing monoclonal antibody, rituximab, to cyclophosphamide, hydroxydaunomycin, Oncovin, and prednisone (CHOP) therapy in non-Hodgkin's lymphoma increases the overall response without increasing toxicities (Weiner, 2010). Another example of this has been shown to between anticancer drugs edatrexate and cisplatin as well as methotrexate and cisplatin, resulting in the ability to use lower doses of each drug in combination while maintaining the same cell death levels as when using higher doses of these drugs individually (Chou et al., 1993). Herceptin has been shown to synergistically interact with both doxorubicin and paclitaxel, though cardiotoxicity risk is increased in combination therapy (Pegram et al., 2000). There are a number of examples of clinical synergy in the area of cancer treatment, often established between established chemotherapy agents and agents representing other classes. If two drugs act synergistically, lower doses of each drug could potentially be used which could allow for less adverse effects while still provided the desired outcome, such as cancer cell death. This potentially allows for maximizing the therapeutic effect while minimizing the adverse effect, or side effects, upon being treated with a given drug regimen (Greco et al., 1996 Foucquier and Guedj, 2015). This is particularly true in cancer treatment. This is because many diseases require treatment that consists of “cocktails,” or mixtures of various drugs taken at once. Synergy is most often defined in relation to the realms of pharmacology and medicine. Unfortunately, in practice, it is far from that simple to quantify such interactions. Now, going back to the 1 + 0 = 2 analogy (Berthoud, 2013 Geary, 2013), it can be asserted that there is a synergistic interaction occurring. Synergy is commonly defined as the effect of two or more agents working in combination that is greater than the expected additive effect of said agents (Greco et al., 1996). However, that paradigm is a very basic analogy for understanding synergist interactions, or synergy. So, it's very counterintuitive to say 1 + 0 = 2, 0 + 0 = 1, or even 1 + 1 = 0. The idea that 1 + 1 = 2 is not novel and virtually agreed upon and understood throughout various academic disciplines and even different cultures around the world. Finally, we describe how methods development and terminology have developed among disciplines outside of biomedicine and pharmacology, to synthesize the literature for readers. We also discuss advantages and limitations to each method, with a focus on the Chou-Talalay Combination Index method. We then review the most common methodology for detection and quantification of synergy, including the two most prominent reference models for describing additive interactions: Loewe Additivity and Bliss Independence. In this review, we first discuss the various terminology surrounding the idea of synergy, providing a comprehensive list of terms defined across numerous disciplines. However, the idea of synergy is not limited to only the biomedical realm and these ideas have developed across many different disciplines, as well. As complex diseases, especially cancer, are being treated with various drug cocktails, understanding the interactions among these drugs is increasingly vital to ensuring successful treatment regimens. The idea of synergistic interactions between drugs and chemicals has been an important issue in the biomedical world for over a century. Lights are especially helpful if you have no choice but to have a light source behind you such as an open window. Yamaha's Easy Set Up wizards and automatic technologies simplify implementation, device configuration, and room acoustics by providing all components required for a successful installation, reducing cost, time, and complexities. Wireless microphones can be very useful for presentation/lecture capture, when the presenter requires freedom of movement.Ī family of products engineered to be installed easily and work together seamlessly, providing unified and customizable communications solutions. The ADECIA Dante-enabled wireless microphone & line array speaker solution satisfies the demand for high-quality wireless audio for office spaces and classrooms. Equipped with nine microphones that perform real beam forming plus an innovative downward-facing speaker for amplified performance, Table takes the quality of your meetings to the next level. Optimized for tabletops and flat surfaces, Stem Table is a high-quality conferencing speakerphone that turns any environment into a professional conference room.
You can get Space Black on both the 14-inch and 16-inch MacBook Pros, but only with an M3 Pro or M3 Max chip. It introduced the new Space Black color to the MacBook Pro, but you can’t get it on every model. Apple is doing something strange with its M3 MacBook Pros, though. Pick the one you like, and you’re on your way. Normally, color options aren’t a big deal on the MacBook Pro. You’ll spend $7,200 for the top M3 Max, 128GB of Unified Memory, and 8TB of storage. In addition, you can pack in up to 8TB of storage for an extra $2,400.Īlthough the 16-inch MacBook Pro starts at a much higher price, it’s not too much more than the 14-inch MacBook when it’s maxed out. Both the M3 Max configurations start with 48GB of memory, and they can scale up to 128GB of memory for an extra $1,000. The former will run you an extra $400 compared to the $2,500 base model, while the latter clocks in at an extra $700. To get 36GB of memory, you’ll need to spend an extra $400, and for 4TB of storage, where the M3 Pro maxes out, you’ll spend an extra $1,200.Īpple offers two configurations of the M3 Max with the 16-inch MacBook Pro, one with a 14-core CPU and 30-core GPU, and another with a 16-core CPU and 40-core GPU. You’ll spend $2,500 for the cheapest model, which comes with the 12-core CPU and 18-core GPU configuration of the M3 Pro, along with 18GB of Unified Memory and and 512GB of storage. The 16-inch model is much more expensive. A fully tricked-out 14-inch MacBook Pro with the highest M3 Max, 128GB of Unified Memory, and 8TB of storage will run you $6,900. The 12-core CPU, 18-core GPU M3 Pro will run you an extra $200 compared to the base model, while the M3 Max with 16 CPU cores and 40 GPU cores will run you an extra $900. Why the MacBook Air is still stuck on the M2 Apple’s M3 Max appears to keep up with Intel’s top desktop CPUĪpple’s new M3 Pro might come with an unexpected downgrade Minimum height: 172 centimetres (5 feet, 6 inches). But in the world of fashion, the region is famous for being home to the most beautiful women in the world. Siberia is known around the world for its frigid temperatures.
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